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Principles. Since Art Art: human skill, craft, or technology, specifically the practice of alchemy in this context is more intricate than Nature (for Nature is "true, plain, patient, constant, etc."), and the Artist Artist: the alchemist or practitioner is more inconstant, impatient, and consequently irregular, the practitioner must necessarily be more subject to error. Consequently, these outcomes are the more difficult to achieve original: "Effect".
Art in all natural productions, though absolutely necessary as an aid, must follow Nature's own pace and way; otherwise, it is more injurious than helpful. However, in artificial things Artificials: products created by human skill rather than occurring spontaneously in nature, a greater latitude original: "Latitude"; meaning freedom of action or scope is granted to the Artist.