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Moffett, Thomas · 1578

they must be mixed with attenuating, diaphoretic, and warming agents, such as wine, pepper, amber, musk, crocus, etc. By which we see the stupefying and cold quality of opium, henbane, and mandrake is diminished, while the sleep-inducing power is actually increased, as if it had obtained a certain vehicle.
Galen, On the Method of Medicine, book 12. Of this kind are Philonium, both sorts, the confection of Lingon, Charicles, and those of Isotheus in Galen, the diacodium of the recent compounders, and Galen's simple poppy syrup of Mesue: which, although it changes the condition of the body somewhat, it is better to choose a change than death, as Galen knows and applies.
These hypnotic compounds, however, must be neither too old nor too new: for the former induce too much sleep, while the latter do not respond to our expectations, to the great danger of the sick person.
The primary efficient cause of anodynes. Finally, so that we may use anodynes more certainly and healthfully, it is appropriate to implore divine help in their application with the most ardent prayers: without which, the sitters-by, the sick person, and the physician all labor in vain: for physicians deprived of God are like other