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The disposition of the patient, a suitable agent, and the contact of both contribute to the putrefaction of the same.
The patient is not disposed [to it] if they are either too sluggish or too cold. Hence, the elderly are more rarely seized by lethargy.
A suitable agent is the heat of the environment οἰκεῖος (congenial), which evokes ϑερμότητα (heat) from the humors. This is increased either by itself or accidentally, namely, through the obstruction of the passages, cold constricting and preventing perspiration.
Diagnostic signs are derived principally from impaired functions, altered excrements, and accidents.
From impaired functions: extreme somnolence, stupidity, forgetfulness, prolapse toward the feet, a pulse that is large, rare, and slow, rare respiration, and trembling of the hands. From altered excrement: phlegm flowing from the eyes, ears, nostrils, and mouth; urine for the most part turbid. From accidents: a discolored face, swollen eyes, pendulous cheeks, and a slow fever increasing daily.
In general, every lethargy is dangerous because it is acute. Specifically, however, that which supervenes upon phrenitis is almost ἀνίατος (incurable).
The magnitude of the same is demonstrated by the vehemence of the symptoms, such as difficult respiration, turbid urine, a looser bowel, and a supervening tremor. 7. Aph. 20.
Because lethargy is a disease, it indicates its own removal through contraries. It cannot, however, be removed by itself, but [only] accidentally,